H. LEONARD JONES JR.; FREDERICK E. WETZEL; BOYD K. BLACK
This case of sickle cell anemia with autopsy is considered worthy of reporting because of the following unusual features: (1) the symptomatology simulating coronary occlusion, with gross electrocardiographic evidence compatible with this condition, in the absence of any histopathologic evidence of myocardial damage other than simple cardiac hypertrophy and dilatation with moderate interstitial edema; (2) the marked sickling of erythrocytes even in the usual blood smear; (3) the coexistence of duodenal ulcer which evoked abdominal pain simulating that often seen in hemolytic crises of sickle cell anemia; (4) the extraordinarily small size of the spleen (5 grams).
JONES HL, WETZEL FE, BLACK BK. SICKLE CELL ANEMIA WITH STRIKING ELECTROCARDIOGRAPHIC ABNORMALITIES AND OTHER UNUSUAL FEATURES, WITH AUTOPSY(SICKLE CELL ANEMIA WITH STRIKING ELECTROCARDIOGRAPHIC ABNORMALITIES AND OTHER UNUSUAL FEATURES, WITH AUTOPSY*). Ann Intern Med. 1948;29:928–935. doi: 10.7326/0003-4819-29-5-928
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Published: Ann Intern Med. 1948;29(5):928-935.
Cardiac Diagnosis and Imaging, Cardiology, Hematology/Oncology, Red Cell Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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