ALFRED J. NIEDERMAYER, M.D.; THOMAS J. MORAN, M.D.
Relapsing febrile nodular nonsuppurative panniculitis (Weber-Christian's disease) is a rare clinical syndrome which was first described by Pfeiffer1 in 1892. Subsequent reports, including one by Weber2 who added the word febrile to the name, brought the number of cases known at present to 29.
As the name implies, this is a chronic recurrent condition, characterized by attacks of fever associated with nonsuppurating nodules in the subcutaneous fatty tissue. The most common localization is in the lower extremities, and of the 29 cases reported in the literature, 24 have been found in women and only five in men.
The condition occurs
NIEDERMAYER AJ, MORAN TJ. RELAPSING FEBRILE NODULAR NONSUPPURATIVE PANNICULITIS: REPORT OF CASE TREATED WITH PENICILLIN1. Ann Intern Med. 1948;29:958–964. doi: 10.7326/0003-4819-29-5-958
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Published: Ann Intern Med. 1948;29(5):958-964.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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