J. E. TETHER, M.D.
The diagnosis of myasthenia gravis has been made with ever increasing frequency since 1935 when Walker1 demonstrated the remarkable therapeutic effect of neostigmine and Viets and Schwab2 described its diagnostic use.
Prior to 1942 there were only four cases on our records. In the past five years 23 more have been diagnosed. These cases will be reported later. The purpose of this paper is to present a modification of the neostigmine diagnostic test described by Schwab and Viets.3 Their test consists of the intramuscular injection of 1.5 mg. of neostigmine methylsulfate combined with 0.6 mg. of atropine sulfate in a
TETHER JE. INTRAVENOUS NEOSTIGMINE IN DIAGNOSIS OF MYASTHENIA GRAVIS1. Ann Intern Med. ;29:1132–1138. doi: 10.7326/0003-4819-29-6-1132
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Published: Ann Intern Med. 1948;29(6):1132-1138.
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