D. SCHERF, F.A.C.P.; A. M. SILVER; L. D. WEINBERG
Although there has been considerable progress in therapy recently, new remedies for the treatment of cardiac arrhythmias deserve attention. Anyone who has seen a patient die as the result of persistently rapid heart rate in a paroxysmal tachycardia, refractory to digitalis, quinidine, and other drugs even in large doses, will welcome a new therapeutic agent.
Alpha-fagarine hydrochloride2 an alkaloid extracted from the Argentinean plant Fagara coco, has been recommended for certain disturbances of stimulus formation.1 It has been used in man,10, 11 and available reports suggested that further studies of the drug were justified.
During the clinical use of
SCHERF D, SILVER AM, WEINBERG LD. CLINICAL OBSERVATIONS WITH FAGARINE1. Ann Intern Med. ;30:100–120. doi: 10.7326/0003-4819-30-1-100
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Published: Ann Intern Med. 1949;30(1):100-120.
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