ARTHUR C. CURTIS, M.D., F.A.C.P.; S. F. HORNE, M.D.
Disseminated lupus erythematosus, although not a common disease, is more frequently recognized than in the past, and as more and more observations are recorded, it becomes apparent that it represents a syndrome in which there may be varying visceral and cutaneous manifestations. It is essentially a diffuse vascular disease involving the small vessels of the skin and viscera, although recent studies1 in which fibrinoid degeneration and sclerosis of the collagen are described as the fundamental change in lupus erythematosus indicate that the concept of a diffuse disease of the peripheral circulation can no longer be entertained without question.
CURTIS AC, HORNE SF. DISSEMINATED LUPUS ERYTHEMATOSUS WITH PERICARDIAL EFFUSION1. Ann Intern Med. ;30:209–217. doi: 10.7326/0003-4819-30-1-209
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Published: Ann Intern Med. 1949;30(1):209-217.
Lupus Erythematosus, Rheumatology.
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