SAMUEL J. SCHNEIERSON, M.D., F.A.C.P.; LOUIS SCHNEIDER, M.D.
Largely as a result of the contributions of Hand,1 Schüller,2 and Christian,3 "xanthomatosis" of the skeletal type became clearly established as a disease found principally in children. The clinical manifestations of the peculiar pathological process were described as defects in membranous bones, exophthalmos and diabetes insipidus, and were all attributable to "xanthomatous" involvement of membranous bones (chiefly skull) and of the hypothalamus. Since these early case reports, the same pathological process has been found in other patients, not a few of them adults. It seems obvious now that the earlier cases with skull defects, exophthalmos and diabetes insipidus represented merely
SCHNEIERSON SJ, SCHNEIDER L. LIPOID GRANULOMATOSIS (XANTHOMATOSIS) WITH MARKED PULMONARY FIBROSIS AND COR PULMONALE AS OUTSTANDING MANIFESTATIONS1. Ann Intern Med. ;30:842–851. doi: 10.7326/0003-4819-30-4-842
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Published: Ann Intern Med. 1949;30(4):842-851.
Interstitial Lung Disease, Pulmonary/Critical Care.
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