E. B. ASTWOOD, M.D., F.A.C.P.
As more is learned about the thyroid gland the more plausible is the concept that goiter is a compensatory enlargement consequent to some interference with normal thyroid function. The subject of continuing debate, however, relates to the relative importance of the numerous factors which are known to be or which are suspected of being concerned in thyroid hormone synthesis. While there can be no question of the fact that iodine is an essential dietary ingredient; and, while it is well established that iodine deficiency is a cause of simple goiter, there is reason to believe that goiter is not always
ASTWOOD EB. THE NATURAL OCCURRENCE OF ANTITHYROID COMPOUNDS AS A CAUSE OF SIMPLE GOITER1. Ann Intern Med. ;30:1087–1103. doi: 10.7326/0003-4819-30-6-1087
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Published: Ann Intern Med. 1949;30(6):1087-1103.
Endocrine and Metabolism, Thyroid Disorders.
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