ROBERT WALL, M.D.; OLIVER BRUNDAGE, M.D.
The use of penicillin with and without heparin in the treatment of subacute bacterial endocarditis has justified the hope for temporary or permanent arrest of this disease. The addition of sodium para-aminohippurate as an enhancing agent may increase the effectiveness of penicillin therapy. Its use with penicillin in the treatment of subacute bacterial endocarditis has been reported by Loewe1 and others with evident success.
Our patient was thought worthy of report because of: (1) the finding of a relatively resistant organism identified as Streptococcus viridans, (2) the large quantities of penicillin and para-aminohippurate administered, and (3) the apparent success of
WALL R, BRUNDAGE O. THE TREATMENT OF SUBACUTE BACTERIAL ENDOCARDITIS WITH PENICILLIN AND SODIUM PARA-AMINOHIPPURATE BY CONTINUOUS INTRAVENOUS DRIP(THE TREATMENT OF SUBACUTE BACTERIAL ENDOCARDITIS WITH PENICILLIN AND SODIUM PARA-AMINOHIPPURATE BY CONTINUOUS INTRAVENOUS DRIP*). Ann Intern Med. 1949;30:1295–1300. doi: 10.7326/0003-4819-30-6-1295
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Published: Ann Intern Med. 1949;30(6):1295-1300.
Cardiology, Endocarditis, Infectious Disease, Streptococcal Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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