HENRY PACKER, M.D., F.A.C.P.; Y. T. WONG, M.D.
The demonstration of favorable results with the use of penicillin in the treatment of tabes dorsalis, shortly after the introduction of this drug in the treatment of syphilis, was of special interest, in view of the highly complex and uncertain origin of the clinical manifestations of this disease. Stokes et al.1 reported in 1944 that improvement in lightning pains following treatment with penicillin occurred in four of seven patients with this symptom. Subsequently Gammon et al.2 reporting on a larger series, found that 66 per cent of tabetic patients with abnormal spinal fluids showed improvement in spinal fluid following penicillin
PACKER H, WONG YT. PENICILLIN AND PENICILLIN-MALARIA IN THE TREATMENT OF TABES DORSALIS1. Ann Intern Med. ;31:96–104. doi: 10.7326/0003-4819-31-1-96
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Published: Ann Intern Med. 1949;31(1):96-104.
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