DAVID C. DAHLIN, M.D.
Slightly more than 100 years ago, Rokitansky1 described a disease in which the organs were infiltrated by a firm, waxy, homogeneous material. Since then, a large volume of literature has concerned itself with this disease process. Early writers, notably Wilks,2 included other conditions, then not understood, under the general category of lardaceous disease. This condition was also called "bacony" or "waxy" degeneration. Virchow3 observed that the infiltrating material in lardaceous disease becomes blue-black on the application of iodine followed by dilute sulfuric acid. Because of this similarity to vegetable starch, he suggested that the substance be called "amyloid."
DAHLIN DC. SECONDARY AMYLOIDOSIS1. Ann Intern Med. ;31:105–119. doi: 10.7326/0003-4819-31-1-105
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Published: Ann Intern Med. 1949;31(1):105-119.
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