CLEMENT S. DWYER, M.D.; SANFORD KRONENBERG, M.D.; MEYER SAKLAD, M.D.
The introduction into experimental clinical medicine of agents which take part in the oxidation-reduction systems of the body has stimulated the interest of clinicians in tissue metabolism and its mechanisms. Succinic acid salts have been discussed in the literature from the standpoint of their effects on oxidative processes in vitro and in the living animal. Various investigators are studying their possible application in the treatment of certain conditions, notably barbiturate intoxication and anesthesia,1, 2, 3, 4, 5, 6 hypoxia,7, 8 and rheumatic fever,9 but the bibliography pertaining to their use is still meager.
Comprehensive evaluation of such agents requires a
DWYER CS, KRONENBERG S, SAKLAD M. ANGINAL SYNDROME DURING SODIUM SUCCINATE THERAPY1. Ann Intern Med. 1949;31:148–153. doi: 10.7326/0003-4819-31-1-148
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Published: Ann Intern Med. 1949;31(1):148-153.
Cardiology, Coronary Heart Disease.
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