G. E. WAKERLIN, Ph.D., M.D., F.A.C.P.
By essential hypertension, of course, is meant chronic hypertension of unknown cause. Approximately 90 per cent of all hypertensions seen clinically belong to this group. The hypertensions of known causes include those associated with nephritis, pyelonephritis, renal anomalies, renal tumors, pheochromocytomas, adrenal cortical tumors, pituitary basophilism, coarctation of the aorta, and certain lesions of the central nervous system. The exact mechanism of the increase in arterial blood pressure in even this latter group, however, is definitely known only in the case of pheochromocytomas; viz., an increased secretion of epinephrine. Nevertheless, clinical differentiation of these hypertensions from essential hypertension is vitally
WAKERLIN GE. RECENT ADVANCES IN THE PATHOGENESIS AND TREATMENT OF ESSENTIAL HYPERTENSION1. Ann Intern Med. 1949;31:312–318. doi: 10.7326/0003-4819-31-2-312
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Published: Ann Intern Med. 1949;31(2):312-318.
Cardiology, Coronary Risk Factors, Hypertension, Nephrology.
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