DAVID T. SMITH, M.D., F.A.C.P.
Although sporadic cases of blastomycosis are found throughout the United States and Canada, the disease has been reported most frequently from the Mississippi Valley and the southeastern states. Durham, N. C. is near the center of the southeastern endemic area and over 50 cases have been studied in the Duke clinic in the past 18 years.
Approximately 45 per cent of the infections were confined to the skin, 45 per cent invaded the internal organs and, in 10 per cent, both the skin and internal organs were involved.
The prognosis seems to depend, at least in part, upon the immunologic
SMITH DT. IMMUNOLOGIC TYPES OF BLASTOMYCOSIS: A REPORT ON 40 CASES1. Ann Intern Med. ;31:463–469. doi: 10.7326/0003-4819-31-3-463
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Published: Ann Intern Med. 1949;31(3):463-469.
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