WILLIAM S. MIDDLETON, M.D., F.A.C.P.
Renewed interest in the etiology of endocarditis lenta has been a natural by-product of the availability of a series of agents with therapeutic promise. The success attendant upon the use of penicillin in treating Streptococcus viridans endocarditis lenta gave further impetus to similar attacks upon other etiologic backgrounds. Among these, Hemophilus influenzae and para-influenzae invited particular attention by reason of their sensitivity to streptomycin.
The incidence of Hemophilus influenzae and para-influenzae endocarditis is probably less common than Thayer's 2.94 per cent.1 In 1940 Craven, Poston and Orgain2 collected only 36 instances of this condition from the literature, to which they
MIDDLETON WS. STREPTOMYCIN THERAPY OF HEMOPHILUS INFLUENZAE ENDOCARDITIS LENTA1. Ann Intern Med. ;31:511–513. doi: 10.7326/0003-4819-31-3-511
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Published: Ann Intern Med. 1949;31(3):511-513.
Cardiology, Endocarditis, Infectious Disease, Streptococcal Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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