H. M. MARGOLIS, M.D., F.A.C.P.; PAUL S. CAPLAN, M.D.
The present report records our preliminary observations in a consecutive series of 58 cases of various types of rheumatic disease in which treatment with curare in oil and wax was instituted. Curare was administered in 51 cases in which muscle spasm actually existed. The remaining seven cases were those in which a diagnosis of psychogenic rheumatism was made. In these, subjective symptoms of "muscle stiffness" without objectively demonstrable spasm were prominent along with many other bizarre musculoskeletal symptoms. Curare was used in this group primarily for control purposes, as an aid in evaluation of results in the larger group. Although
MARGOLIS HM, CAPLAN PS. THE USE OF CURARE (D-TUBOCURARINE IN OIL AND WAX) IN THE TREATMENT OF MUSCLE SPASM IN RHEUMATIC DISORDERS1. Ann Intern Med. ;31:615–623. doi: 10.7326/0003-4819-31-4-615
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Published: Ann Intern Med. 1949;31(4):615-623.
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