NATHANIEL UHR; JACOB CHURG
Much knowledge regarding the clinical aspects of hypertrophic osteoarthropathy has been acquired in the past half century. Its etiology and mechanism, however, remain to be elucidated. In the majority of cases, osteoarthropathy, with its concomitant clubbing of the fingers and toes, is seen as a sequel of chronic suppurative or neoplastic disease of the thoracic organs, less commonly of the abdominal viscera. Only in rare instances has the condition been known to precede the manifestation of the underlying disease. When this occurs, diagnosis is often impossible until late. The following is an illustrative case.
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UHR N, CHURG J. HYPERTROPHIC OSTEOARTHROPATHY; REPORT OF A CASE ASSOCIATED WITH A CHORDOMA OF THE BASE OF THE SKULL AND LYMPHANGITIC PULMONARY METASTASES1. Ann Intern Med. ;31:681–691. doi: 10.7326/0003-4819-31-4-681
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Published: Ann Intern Med. 1949;31(4):681-691.
Hematology/Oncology, Lung Cancer, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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