J. M. SPITZER, M.D.; NORMAN ROSENTHAL, M.D.; MURRAY WEINER, M.D.; SHEPARD SHAPIRO, M.D.
The most dangerous complication of venous thrombosis is pulmonary embolism, with its mortality of about 20 per cent.1 Such embolism has been reported by Barnes3 to be responsible for 34,000 deaths in this country each year. Knauer2 has reported fatal pulmonary embolism in 2.5 per cent of 33,558 autopsies. Hunter4 found that over 50 per cent of older people confined to bed evidenced thrombosis of the deep leg veins, with pulmonary emboli from these veins accounting for over 3 per cent of all deaths.
The factors which determine whether a thrombus will or will not embolize are not fully understood.
SPITZER JM, ROSENTHAL N, WEINER M, SHAPIRO S. PULMONARY EMBOLISM: ITS INCIDENCE AT NECROPSY IN RELATION TO PERIPHERAL THROMBOSIS1. Ann Intern Med. ;31:884–888. doi: 10.7326/0003-4819-31-5-884
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Published: Ann Intern Med. 1949;31(5):884-888.
Emergency Medicine, Pulmonary Embolism, Pulmonary/Critical Care, Venous Thromboembolism.
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