ISIDORE S. EDELMAN, M.D.
Transverse interruption of spinal cord function occurs relatively infrequently as a result of metastases from carcinoma of the prostate. Bumpus1 reported that 11 of 1,000 untreated patients with carcinoma of the prostate had symptoms simulating tumor of the cord with some paralysis prior to death. In those patients with cord compression by metastatic tumor and loss of motor power, loss of sphincteric control and associated ascending urinary tract infection, palliation becomes a problem of prime importance.
The beneficial palliative effects of orchiectomy and/or estrogenic therapy in the treatment of advanced prostatic carcinoma are well known.2, 3, 4, 5, 6
EDELMAN IS. PARAPLEGIA SECONDARY TO METASTATIC PROSTATIC CARCINOMA TREATED WITH STILBESTROL: REPORT OF A CASE1. Ann Intern Med. ;31:1098–1102. doi: 10.7326/0003-4819-31-6-1098
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Published: Ann Intern Med. 1949;31(6):1098-1102.
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