DEWITT STETTEN JR.
When the chemist approaches the study of a biological system, his first enquiry is usually at the analytical level, namely, the identification and quantitative determination of the reactants. Having answered these purely analytical questions, he must next undertake the pursuit of more elusive matters. What reactions do these reactants undergo in the body? How are they formed, and how destroyed? What are the normal rates of these several reactions, and how do these rates vary in response to such variables as growth, disease, drug action and altered nutrition?
It is unfortunate that the answers to such questions cannot, in general,
STETTEN D. THE USE OF ISOTOPES AS METABOLIC TRACERS1. Ann Intern Med. ;32:1–5. doi: 10.7326/0003-4819-32-1-1
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Published: Ann Intern Med. 1950;32(1):1-5.
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