H. ST. GEORGE TUCKER JR., M.D.; JAMES L. CHITWOOD, M.D.; CARL P. PARKER JR., M.D.
In 1940 Means, Hertz and Lerman1 described a group of patients with myxedema who did not respond well to thyroid treatment. When the usual doses of desiccated thyroid were given, the patients became weaker, and in some the picture of adrenal insufficiency developed. It was shown that in these patients myxedema was only part of a more widespread glandular failure resulting from primary insufficiency of the anterior pituitary gland. The name "pituitary myxedema" was suggested for this condition. Similar cases have been reported by other authors.2-8
Pituitary myxedema may be regarded as a special type of anterior pituitary failure or
TUCKER HSG, CHITWOOD JL, PARKER CP. PITUITARY MYXEDEMA: REPORT OF THREE CASES1. Ann Intern Med. ;32:52–62. doi: 10.7326/0003-4819-32-1-52
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Published: Ann Intern Med. 1950;32(1):52-62.
Endocrine and Metabolism, Thyroid Disorders.
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