AXEL M. HJORT, M.D., Ph.D., F.A.C.P.; ANN S. WORDEN, A.B.; JEAN HOGLE, A.B.
The current consensus leans to the view that serological reactions play an important, if not essential, rôle in initiating allergic events, and that the subsequent elaboration of histamine or a histamine-like substance, completes them. Some believe the above is not the whole story, and that other factors contribute to complete the allergic phenomenon, i.e., the possible part played by the vegetative nervous system and by altered tissue states. Many theoretical and factual observations have been made during the past generation in support of these views. Many facets of the picture have been explored, but others remain for consideration or elaboration.
HJORT AM, WORDEN AS, HOGLE J. EVALUATION OF HISTAMINE AND CHOLINESTERASE IN ALLERGIC PHENOMENA1. Ann Intern Med. ;32:217–228. doi: 10.7326/0003-4819-32-2-217
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Published: Ann Intern Med. 1950;32(2):217-228.
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