ANNETTE C. WASHBURNE, M.D., F.A.C.P.
The increasing scope of psychosomatic medicine has reëmphasized the inter-relationship of psyche and soma in the production of various pathologic disorders.
Alterations in certain physiologic processes are evident in such conditions as schizophrenia, manic depressive reactions, benign depressions, and tension-anxiety states. Among these alterations, changes in body temperature, endocrine functions, biochemical factors, and the circulatory system have been observed. Investigations have suggested that such alterations may prove of etiologic significance in the production of certain of the above mentioned syndromes. These investigations, while highly interesting, have on the whole been inconclusive and not infrequently at variance. These contradictions, although
ANNETTE C. WASHBURNE. NICOTINIC ACID IN THE TREATMENT OF CERTAIN DEPRESSED STATES: A PRELIMINARY REPORT(NICOTINIC ACID IN THE TREATMENT OF CERTAIN DEPRESSED STATES: A PRELIMINARY REPORT*). Ann Intern Med. 1950;32:261–269. doi: 10.7326/0003-4819-32-2-261
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Published: Ann Intern Med. 1950;32(2):261-269.
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