HENRY ALEXANDER BRADFORD, M.D., F.A.C.P.; LEIGHTON L. ANDERSON, M.D.
Myocarditis,1, 2 although infrequent, has been found in several virus diseases. In 1942, Saphir and Wile3 described inflammatory changes in the hearts of six patients, from a series of seven, dying of poliomyelitis. The hearts of this series of patients were described grossly as "slightly dilated but not hypertrophied . . . the myocardium was slightly flabby, usually grayish red." Interesting microscopic findings were noted. The perivascular spaces were infiltrated with lymphocytes and neutrophiles in variable numbers—monocytes were present in lesser degree. In half of the cases where the myocardial changes were more severe, there were additional histological features; the
BRADFORD HA, ANDERSON LL. ELECTROCARDIOGRAPHIC OBSERVATIONS DURING A POLIOMYELITIS EPIDEMIC1. Ann Intern Med. ;32:270–278. doi: 10.7326/0003-4819-32-2-270
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Published: Ann Intern Med. 1950;32(2):270-278.
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