H. MILTON ROGERS, M.D., F.A.C.P.; FRANCIS H. LANGLEY, M.D.
The syndrome of atrophic polyarthritis occurring in an adult, associated with fever, secondary anemia, leukopenia and splenomegaly, was described by Felty1 in 1924. Chevallier2 suggested in 1930 that splenectomy might produce relief of the arthritis in Felty's syndrome. This surgical procedure, however, was not performed until 1932, when Hanrahan and Miller3 reported the first case of Felty's syndrome in which splenectomy was performed for the neutropenia and splenomegaly. Subsequent cases of the syndrome under discussion in which splenectomy was performed were reported by Craven4; Reich5; Bloem, van Creveld, Kuipers and Zuidema6; Steinberg7; Gyntelberg8; Trolle and Trolle9; Dameshek10; Zimmer11; Hirschboeck12 (two
ROGERS HM, LANGLEY FH. NEUTROPENIA ASSOCIATED WITH SPLENOMEGALY AND ATROPHIC ARTHRITIS (FELTY'S SYNDROME): REPORT OF A CASE IN WHICH SPLENECTOMY WAS PERFORMED1. Ann Intern Med. 1950;32:745–754. doi: 10.7326/0003-4819-32-4-745
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Published: Ann Intern Med. 1950;32(4):745-754.
Rheumatoid Arthritis, Rheumatology.
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