HENRY J. L. MARRIOTT, B.M. (Oxon.); H. RAYMOND PETERS, M.D., F.A.C.P.
Hematologic reactions are among the rarer, but more serious results of chrysotherapy; of these thrombocytopenia is by far the commonest. Granulocytopenia and aplastic anemia have been reported less frequently. Of the three dyscrasias aplastic anemia has proved most fatal.
Thrombocytopenia. More cases of hemorrhagic purpura than of any other blood disorder have been recorded following gold administration. It is remarkable that in many reports platelet counts are not given, and so thrombocytopenia, in some cases, can only be assumed.
Emile-Weil1 reported one case of hemorrhagic purpura in 1931; he and Bousser2 later referred to 30 instances of "hemorrhagic accidents," but
MARRIOTT HJL, PETERS HR. BLOOD DYSCRASIAS SECONDARY TO GOLD: WITH A CASE OF HYPOPLASTIC ANEMIA CURED BY SPLENECTOMY1. Ann Intern Med. ;32:864–877. doi: 10.7326/0003-4819-32-5-864
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Published: Ann Intern Med. 1950;32(5):864-877.
Hematology/Oncology, Red Cell Disorders.
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