EDWARD S. ORGAIN, M.D., F.A.C.P.; CHARLES K. DONEGAN, M.D.
During the last decade, the introduction and practical application of new chemical and antibiotic agents in the therapy of bacterial endocarditis have altered completely the outlook in this disease which formerly was considered to be almost universally fatal. Prior to the advent of the various sulfonamide compounds, no specific therapeutic agents were available, and spontaneous recoveries ranged about 1 per cent or less. In the years 1937 to 1943, the sulfonamide drugs, alone and with supplementary forms of treatment, provided cures in but 5.5 per cent of a large series of cases collected by Lichtman.1 In 1943, the National Research
EDWARD S. ORGAIN, CHARLES K. DONEGAN. THE TREATMENT OF BACTERIAL ENDOCARDITIS(THE TREATMENT OF BACTERIAL ENDOCARDITIS*). Ann Intern Med. 1950;32:1099–1113. doi: 10.7326/0003-4819-32-6-1099
Download citation file:
Published: Ann Intern Med. 1950;32(6):1099-1113.
Cardiology, Endocarditis, Infectious Disease.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use