J. A. VAICHULIS, Ph.D.; A. LITTMAN, M.D.; A. C. IVY, Ph.D., M.D., F.A.C.P.; G. ZUBOWICZ, M.D.; R. KAPLAN, M.D.
The treatment of chronic typhoid carriers is an important public health problem. Hundreds of non-surgical methods of therapy have been tried and found ineffective.
While cholecystectomy results in the cure of 70 per cent or more of biliary carriers, there are patients who refuse or who are too ill for this operation. There are also many extra-cholecystic carriers. Although the morbidity and mortality incident to cholecystectomy are low in many surgical clinics, it is undesirable to remove the gall bladder because of an infection which may not have destroyed the functional ability of that organ.
It is the purpose
VAICHULIS JA, LITTMAN A, IVY AC, ZUBOWICZ G, KAPLAN R. THE CHRONIC TYPHOID CARRIER. III. THERAPY WITH ANTAGONISTIC BACILLUS, ANTIBIOTICS AND SULFONAMIDES1. Ann Intern Med. ;33:361–370. doi: 10.7326/0003-4819-33-2-361
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Published: Ann Intern Med. 1950;33(2):361-370.
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