EDWIN D. KILBOURNE, M.D.; J. PHILIP LOGE, M.D.
"Influenza," a term traditionally fraught with ambiguity and even today loosely applied to any acute, benign, febrile illness, is now recognized as a specific viral infection of the upper respiratory tract of man.
The isolation, in 1933, of the specific etiological virus of influenza by Smith, Andrewes and Laidlaw1 made possible for the first time attempts at definition of the clinical syndrome of this disease. Studies by Stuart-Harris et al.,2 during the English epidemic of 1936-1937, established that patients proved to have been infected by influenza A virus presented the characteristic, if not pathognomonic, clinical picture of an abrupt, prostrating
KILBOURNE ED, LOGE JP. INFLUENZA A PRIME: A CLINICAL STUDY OF AN EPIDEMIC CAUSED BY A NEW STRAIN OF VIRUS1. Ann Intern Med. ;33:371–379. doi: 10.7326/0003-4819-33-2-371
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Published: Ann Intern Med. 1950;33(2):371-379.
Infectious Disease, Influenza.
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