PHILIP KRAININ, M.D., F.A.C.P.; BERNARD S. KAHN, M.D.
A recent experience with a patient suffering from hemochromatosis has led us to attempt to correlate modern concepts of iron metabolism with the altered pigment metabolism of this disease. We believe that more fruitful data will be obtained from studies of the intestinal mucosa and enzyme systems present therein than from additional descriptive observations of the end results of pigment metabolism.
The disease is rare; only some 400 cases have been reported. The life span of patients with hemochromatosis has been lengthened, and it is to be hoped, therefore, that further metabolic investigation with radio-iron will be pursued, with attention
KRAININ P, KAHN BS. HEMOCHROMATOSIS: REPORT OF A CASE IN A NEGRO; DISCUSSION OF IRON METABOLISM1. Ann Intern Med. 1950;33:453–462. doi: 10.7326/0003-4819-33-2-453
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Published: Ann Intern Med. 1950;33(2):453-462.
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