BYRON F. ROYCE, M.D.
In 1924, Howard2 stated that 200 cases of syphilis of the lung had been reported in the literature. He felt that this disease could no longer be considered a rarity. The majority of cases reported were from large autopsy series. These reports are reviewed in papers by Hartung and Freedman4; Jacobs8; Hamilton and Wexler10; Lyons, Brogan and Sawyer15; Wilson,21 and Kulchar and Windholz.22 Denman5 and Warring13 stated that syphilis of the lung cannot be definitely diagnosed clinically. These authors considered clinical pulmonary syphilis a rare condition, as did Reynolds and Moore.12 However, cases without autopsy or demonstration of the Spirochaeta
ROYCE BF. THE CRITERIA FOR CLINICAL DIAGNOSIS OF SYPHILIS OF THE LUNG; WITH REPORT OF A CASE1. Ann Intern Med. ;33:700–707. doi: 10.7326/0003-4819-33-3-700
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Published: Ann Intern Med. 1950;33(3):700-707.
Infectious Disease, Pulmonary/Critical Care, Sexually Transmitted Infections.
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