HAROLD A. LYONS
Interest in porphyria has been stimulated of late, by the articles appearing in the literature.1, 2, 3, 4, 5
Exhaustive studies of this subject have been made by Dobriner and Rhoads,1 C. J. Watson,5 Turner,2, 6 and many others.4, 9, 21, 34
The first description of the disease was made by Hoppe-Selye7 in 1871. He discovered that the addition of a strong sulfuric acid to hemoglobin produced a substance with a characteristic absorption spectrum which he called "hematoporphyrin." It was discovered later that this was not the substance excreted in the urine and feces of patients who had porphyria. This
LYONS HA. ACUTE PORPHYRIA WITH SPINAL FLUID CHANGES1. Ann Intern Med. ;33:711–717. doi: 10.7326/0003-4819-33-3-711
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Published: Ann Intern Med. 1950;33(3):711-717.
Gastroenterology/Hepatology, Liver Disease.
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