F. K. BAUER, M.D.; W. CHAMP RILEY, M.D.; ELI B. COHEN, M.D.
It has been established in recent years that both rheumatic fever and disseminated lupus erythematosus are systemic disease entities characterized by lesions involving certain peripheral and central vascular fields. The lesions are similar to those produced in experimental anaphylaxis. Klinge1 demonstrated that these "rheumatic" granulomas, formerly thought to be specific for rheumatic fever, are neither specific nor constant. In rheumatic fever the predominant rôle of streptococci as allergens is undisputed. However, it has also been established that various nonbacterial agents are capable of producing similar characteristic morphologic changes as seen in various disease entities, including rheumatic fever and disseminated lupus
BAUER FK, RILEY WC, COHEN EB. DISSEMINATED LUPUS ERYTHEMATOSUS WITH SYDENHAM'S CHOREA AND RHEUMATIC HEART DISEASE: REPORT OF A CASE WITH AUTOPSY1. Ann Intern Med. ;33:1042–1053. doi: 10.7326/0003-4819-33-4-1042
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Published: Ann Intern Med. 1950;33(4):1042-1053.
Lupus Erythematosus, Neurology, Rheumatology.
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