EDWARD H. KASS, PH.D., M.D.; SIDNEY H. INGBAR, M.D.; MAXWELL FINLAND, M.D., F.A.C.P.
Although adrenal cortical and pituitary adrenocorticotropic hormones have produced remarkable alterations in the course of many clinical disorders,5, 9 the mechanisms by which these changes are induced remain obscure. Immunologic factors have been considered to play an important rôle in the pathogenesis of, or recovery from, many of the diseases in which cortisone and ACTH have exerted apparently beneficial effects. Because adrenal hormones have been implicated in immunologic processes,9, 10 attempts have been made to explain the effects of cortisone and ACTH in terms of immunologic mechanisms. However, it is obviously difficult to study the effects of ACTH on immunologic
KASS EH, INGBAR SH, FINLAND M. EFFECTS OF ADRENOCORTICOTROPIC HORMONE IN PNEUMONIA: CLINICAL, BACTERIOLOGICAL AND SEROLOGICAL STUDIES1. Ann Intern Med. 1950;33:1081–1098. doi: 10.7326/0003-4819-33-5-1081
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Published: Ann Intern Med. 1950;33(5):1081-1098.
Infectious Disease, Pneumonia, Pulmonary/Critical Care.
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