MARTIN H. REINBERG, M.D.; MORRIS LIPSON, M.D.
Recent studies have indicated that the fatty liver represents an early stage in the pathogenesis of Laennec's cirrhosis.1, 2, 3 There is evidence of an increased amount of fat in the livers of diabetic animals4, 5 and of uncontrolled diabetic patients.6, 7 Thus the incidence of Laennec's cirrhosis associated with diabetes mellitus is of some interest.
Enlargement of the liver is considered to be common in diabetic patients and almost invariable in those with diabetic acidosis.1 It has been assumed that the hepatomegaly is due primarily to gross fatty infiltration.7, 8 Unfortunately, liver size must be estimated by its clinical
REINBERG MH, LIPSON M. THE ASSOCIATION OF LAENNEC'S CIRRHOSIS WITH DIABETES MELLITUS1. Ann Intern Med. ;33:1195–1202. doi: 10.7326/0003-4819-33-5-1195
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Published: Ann Intern Med. 1950;33(5):1195-1202.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism, Gastroenterology/Hepatology.
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