SAMUEL MARTON, M.D., F.A.C.A.
Almost every physician in his daily practice meets some variety of allergic manifestation which requires relief or palliation. Of late, the antihistaminic drugs have come into prominence because of their ability to alleviate this condition. Unfortunately, the unpleasant side reactions which frequently accompany their use sometimes necessitate their discontinuance. Investigations therefore continue for a more effective and less toxic antagonist to histamine which would demonstrate fewer side reactions.
The writer had the opportunity to procure one of the newer antihistaminics, Diatrin Hydrochloride,2 for investigation. It was felt that, to evaluate clinically its therapeutic effectiveness and possible side reactions, more accurate
MARTON S. DIATRIN, A NEW ANTIHISTAMINIC WITH MINIMAL SIDE REACTIONS1. Ann Intern Med. ;33:1444–1449. doi: 10.7326/0003-4819-33-6-1444
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Published: Ann Intern Med. 1950;33(6):1444-1449.
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