IRVING LEINWAND, M.D.
Since Buschke1 in 1900 described the syndrome designated as scleredema adultorum there have been 99 cases reported in the literature collected and reviewed by Vallee,2 to which he added four. One autopsied case had been reported by Stenbeck3 (1940), in which he noted visceral lesions resembling those found in the skin. In view of the overwhelming preponderance of recoveries in this disease, some doubts have been expressed as to the diagnosis of a true scleredema in that case: although the clinical picture resembled scleredema, a review of the pathologic report suggests a diagnosis of scleroderma.
The systemic nature of scleredema
LEINWAND I. GENERALIZED SCLEREDEMA: REPORT WITH AUTOPSY FINDINGS1. Ann Intern Med. ;34:226–238. doi: 10.7326/0003-4819-34-1-226
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Published: Ann Intern Med. 1951;34(1):226-238.
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