ESTELLE E. KLEIBER, M.D., F.A.C.P.; GABRIEL PICKAR, M.D.
In recent years, studies of heart failure have stressed the fact that, when cardiac output is inadequate for tissue needs, the body compensates by increasing the blood volume and the tissue fluid volume. Since in most cases kidney function is reasonably good, tubular absorption of sodium is complete and retention occurs. The problem of increasing the excretion of sodium has therefore become of primary importance in the clinical treatment of congestive failure. Together with digitalization, salts such as ammonium chloride, mercurial diuretics and strict low sodium diets have become the mainstay of treatment. In addition, salt restriction with or without
KLEIBER EE, PICKAR G. TREATMENT OF CHRONIC CONGESTIVE CARDIAC FAILURE WITH ION EXCHANGE RESINS1. Ann Intern Med. 1951;34:407–414. doi: 10.7326/0003-4819-34-2-407
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Published: Ann Intern Med. 1951;34(2):407-414.
Cardiology, Heart Failure.
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