ISIDOR MUFSON, M.D., F.A.C.P.
As reported in a previous paper, radioactive sodium by its introduction into a distant vein and the measurement of its local accumulation in an extremity was utilized to test the efficacy of several drugs commonly used in the treatment of peripheral arterial insufficiency. These included papaverine, 5 per cent solution of sodium chloride, histamine intravenously, and histamine given by intraarterial infusion.6 We are now presenting observations made in a similar manner on the effects produced on peripheral circulation by the intraarterial introduction of aminophylline, papaverine, histamine and adrenalin, the intravenous introduction of Etamon, and the blocking of the lumbar sympathetic
MUFSON I. RESPONSES OF THE ABNORMAL ARTERIAL CIRCULATION TO VARIOUS STIMULI, AS STUDIED BY THE USE OF RADIOACTIVE SODIUM. II. INTRAARTERIAL HISTAMINE, PAPAVERINE, AMINOPHYLLINE AND ADRENALINE; SYMPATHECTOMY AND ETAMON; PAIN1. Ann Intern Med. ;34:428–441. doi: 10.7326/0003-4819-34-2-428
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Published: Ann Intern Med. 1951;34(2):428-441.
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