GEORGE L. NORRIS, M.D.; EDWARD MASSIE, M.D., F.A.C.P.
That respiration changes the contour of the electrocardiogram has been known since Einthoven, Rotherberger, and Winterberg1 studied the shifting electrical axis of the heart and found that sympathetic stimulation or vagal paralysis produced changes similar to those at first thought due solely to the mechanical effects of movement of the diaphragm. Wilson2, 3 in 1915 reported three cases in which respiration was associated with auriculoventricular dissociation, and one instance in which a partially inverted T3 became upright and exaggerated. The same changes were brought about by pressure over the right vagus, and were eliminated by atropine. He emphasized that
NORRIS GL, MASSIE E. THE EFFECT OF A SINGLE INSPIRATION IN LEAD III AND A PRECORDIAL LEAD OF THE HUMAN ELECTROCARDIOGRAM(THE EFFECT OF A SINGLE INSPIRATION IN LEAD III AND A PRECORDIAL LEAD OF THE HUMAN ELECTROCARDIOGRAM*). Ann Intern Med. 1951;34:641–654. doi: 10.7326/0003-4819-34-3-641
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Published: Ann Intern Med. 1951;34(3):641-654.
Cardiac Diagnosis and Imaging, Cardiology.
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