K. E. PASCHKIS; A. CANTAROW
The hypophysectomized animal has proved to be the most valuable preparation in the study of pituitary physiology. Patients with destructive lesions of the anterior pituitary offer an opportunity for similar investigations of the physiology of the human pituitary gland. The studies reported in this paper were undertaken because relatively few such investigations have been published.
The 17 patients studied include cases of pituitary or parapituitary tumors (chromophobe adenomas, craniopharyngiomas) and nontumor cases (table 1). In addition to clinical examination and routine laboratory tests, the following studies were made: basal metabolic rate, serum cholesterol, insulin tolerance test,8 salt
PASCHKIS KE, CANTAROW A. HYPOPITUITARISM: STUDIES IN PITUITARY TUMORS AND SIMMONDS' DISEASE1. Ann Intern Med. ;34:669–677. doi: 10.7326/0003-4819-34-3-669
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Published: Ann Intern Med. 1951;34(3):669-677.
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