W. EDWARD STOREY, M.D.
The tests of urinary dilution and concentration, particularly the latter, are generally regarded as a simple and reliable means of detecting early impairment of renal function. They are based upon the fact that healthy kidneys can adapt, within wide limits, to varying demands for the elimination of water and solids. This adaptability may be observed in the specific gravity of the urine under controlled conditions.
Since the publication, in 1910 of Volhard's1 technic for the performance of these tests, various modifications have appeared.2, 3, 4, 5, 6, 7 While each of these has acquired varying acceptance, that of Fishberg8 is
W. EDWARD STOREY. VARIATIONS IN URINARY DILUTION AND CONCENTRATION AMONG HEALTHY MALES UNDER SIMPLE STANDARD CONDITIONS(VARIATIONS IN URINARY DILUTION AND CONCENTRATION AMONG HEALTHY MALES UNDER SIMPLE STANDARD CONDITIONS*). Ann Intern Med. 1951;34:737–746. doi: 10.7326/0003-4819-34-3-737
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Published: Ann Intern Med. 1951;34(3):737-746.
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