EDWARD H. REISNER JR., M.D.; FREDERICK N. BAILEY, M.D.; EMANUEL APPELBAUM, M.D., F.A.C.P.
In 1945, Johnson, Anker and Meleney1 reported the discovery of an antibiotic which they called bacitracin, produced by the Tracey I strain of B. subtilis. It had a bactericidal spectrum roughly comparable to that of penicillin,2 and was well tolerated by laboratory animals3, 4 when applied locally or injected systemically. In 1947, Meleney and Johnson2 reported the first 100 cases of surgical infections treated locally with bacitracin, with results at least comparable to those obtainable with penicillin. Since then the local use of bacitracin has been successful in the treatment of infections of the skin5 and eye, and bacitracin has
REISNER EH, BAILEY FN, APPELBAUM E. THE TREATMENT OF PNEUMONIA WITH BACITRACIN1. Ann Intern Med. ;34:1232–1242. doi: 10.7326/0003-4819-34-5-1232
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Published: Ann Intern Med. 1951;34(5):1232-1242.
Infectious Disease, Pneumonia, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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