MANDRED W. COMFORT, M.D., F.A.C.P.
Everyone knows that in gastric cancer the mean gastric secretory activity is subnormal, but to what extent is it subnormal? What factors influence gastric acidity in gastric cancer? Does cancer develop in stomachs that already have subnormal gastric acidity, or does gastric secretory function become subnormal after cancer develops? What process is responsible for lowered gastric secretion? Finally, of what diagnostic and prognostic value is the degree of gastric secretory activity?
In the past two decades, many facts bearing on these questions have been recorded. These data will be summarized.
Survey of data from normal
COMFORT MW. GASTRIC ACIDITY BEFORE AND AFTER DEVELOPMENT OF GASTRIC CANCER: ITS ETIOLOGIC, DIAGNOSTIC AND PROGNOSTIC SIGNIFICANCE1. Ann Intern Med. 1951;34:1331–1348. doi: 10.7326/0003-4819-34-6-1331
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Published: Ann Intern Med. 1951;34(6):1331-1348.
Gastric Cancer, Gastroenterology/Hepatology, Gastrointestinal Cancer, Hematology/Oncology.
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