R. WAYNE MOODY, M.D., F.A.C.P.
The availability of crystalline and weighable forms of digitalis has been a great step forward in the treatment of cardiac disease simply because dosage can now be determined with absolute accuracy. With this fact in mind, the majority of the patients in the Colorado General Hospital Outpatient Heart Clinic were placed on digitoxin over two years ago and have been kept on this drug from that time until the present. Digitoxin was chosen because its oral and intravenous dosage is essentially the same. Whether this advantage outweighs its disadvantages, particularly its long period of excretion, remains to be seen.
MOODY RW. MAINTENANCE DOSE AND TOXICITY OF DIGITOXIN1. Ann Intern Med. ;34:1349–1357. doi: 10.7326/0003-4819-34-6-1349
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Published: Ann Intern Med. 1951;34(6):1349-1357.
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