CHARLES R. LOWE, M.D.; DONALD C. OVERY, M.D.
This study was undertaken in an effort to evaluate the possibility of diminishing and preventing the formation of ascites in patients with hepatic cirrhosis by restriction of sodium intake in conjunction with the use of diuretics. If such patients could be spared the discomfort of massive ascites and frequent abdominal paracenteses without causing an unfavorable effect upon their disease in general, the procedure would be considered worthwhile.
In the first decade of the present century, articles appeared in the French literature1, 2, 3 advocating the restriction of sodium chloride in the diet as a means of retarding the formation of
LOWE CR, OVERY DC. AN EVALUATION OF RIGID DIETARY SODIUM RESTRICTION IN THE MANAGEMENT OF ASCITES IN CIRRHOSIS OF THE LIVER1. Ann Intern Med. ;34:1396–1403. doi: 10.7326/0003-4819-34-6-1396
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Published: Ann Intern Med. 1951;34(6):1396-1403.
Gastroenterology/Hepatology, Liver Disease.
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