EDWARD C. RAFFENSPERGER, M.D., F.A.C.P.
It has long been appreciated that the Cherry and Crandall1 modification of the Loevenhart method for determining serum lipase activity, and the Somogyi2 method for determining serum amylase activity, are valuable laboratory procedures for studying intrinsic pancreatic disease. However, elevations of serum pancreatic enzymes in conditions other than intrinsic pancreatic disease occur. It is the purpose of this paper to review the literature on this subject and to report on 21 cases, all of which showed appreciable elevations of serum pancreatic enzyme activity without intrinsic pancreatic disease.
The normal values of serum amylase and serum lipase determined by the methods
RAFFENSPERGER EC. ELEVATED SERUM PANCREATIC ENZYME VALUES WITHOUT PRIMARY INTRINSIC PANCREATIC DISEASE1. Ann Intern Med. ;35:342–351. doi: 10.7326/0003-4819-35-2-342
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Published: Ann Intern Med. 1951;35(2):342-351.
Gastroenterology/Hepatology, Pancreatic Disease.
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