MILTON N. TOWBIN, M.D.
For over a hundred years physicians have recognized that mediastinal emphysema may occur following severe straining, pulmonary disease or trauma of the chest. Laennec1 in 1819 briefly referred to this complication in his first treatise on diseases of the chest, and in 1826 accurately described it under the heading "Emphyséme Interlobulaire du Poumon."2 These observations were later confirmed by Skoda,3 and in 1856 Rokitansky4 explained the pathologic anatomy of this condition resulting from ulceration of the trachea or pulmonary trauma. Müller5 in 1888 discussed its diagnostic features and also postulated a mechanism of production similar
TOWBIN MN. MEDIASTINAL EMPHYSEMA OCCURRING WITH THERAPEUTIC PNEUMOPERITONEUM: REPORT OF TEN CASES1. Ann Intern Med. 1951;35:555–592. doi: 10.7326/0003-4819-35-3-555
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Published: Ann Intern Med. 1951;35(3):555-592.
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