ROBERT F. KLEINSCHMIDT, M.D.; JOHN M. JOHNSTON, M.D., F.A.C.P.
A case of acute miliary tuberculosis in a patient receiving cortisone for a chronic febrile illness with arthritic manifestations has recently been observed by us. We have not been able to find a similar instance reported in the literature, although active tuberculosis has been enhanced and aggravated by administration of cortisone to experimental animals.
Spain and Molomut1 produced tuberculosis in guinea pigs and later treated them respectively with cortisone, with streptomycin, and with a combination of cortisone and streptomycin. Autopsy studies showed the lesions in those receiving cortisone to be more extensive, more widely distributed and less well localized than
KLEINSCHMIDT RF, JOHNSTON JM. MILIARY TUBERCULOSIS IN A CORTISONE TREATED PATIENT: CASE REPORT WITH AUTOPSY1. Ann Intern Med. ;35:694–702. doi: 10.7326/0003-4819-35-3-694
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Published: Ann Intern Med. 1951;35(3):694-702.
Infectious Disease, Mycobacterial Infections.
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