JOSEPH B. KIRSNER, M.D., Ph.D., F.A.C.P.; WALTER L. PALMER, M.D., Ph.D., F.A.C.P.; ERWIN LEVIN, M.A., M.D.; ARTHUR P. KLOTZ, M.D.
The medical management of peptic ulcer in large part comprises the use of compounds which either neutralize or inhibit temporarily the output of hydrochloric acid.1 The rationale of this treatment and evaluation of its therapeutic efficacy are beyond the scope of the present study. The purpose of this paper is rather to survey the current status of antacid and antisecretory drugs with reference primarily to their effects upon gastric secretion in man.
The various procedures for estimating the efficiency of antacid and antisecretory drugs are of limited scope and are
KIRSNER JB, PALMER WL, LEVIN E, KLOTZ AP. GASTRIC ANTACID AND ANTI-SECRETORY DRUGS: A SURVEY BASED PRIMARILY ON THEIR EFFECTS UPON GASTRIC SECRETION IN MAN1. Ann Intern Med. ;35:785–811. doi: 10.7326/0003-4819-35-4-785
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Published: Ann Intern Med. 1951;35(4):785-811.
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