PHILIP S. HENCH, M.D., F.A.C.P.
It may be appropriate to discuss in this Nobel Lecture three general aspects of cortisone and pituitary adrenocorticotropic hormone (ACTH): (1) the development of the theory which eventually led to the use of cortisone and ACTH in rheumatic and certain other conditions; this I shall do in some detail, giving certain data not published heretofore; (2) the present status of cortisone and ACTH in general medicine; this topic I shall discuss summarily in view of the several current reports thereon; and (3) some major requirements for the orderly development of cortisone and ACTH as therapeutic agents; this aspect will be
HENCH PS. THE REVERSIBILITY OF CERTAIN RHEUMATIC AND NONRHEUMATIC CONDITIONS BY THE USE OF CORTISONE OR OF THE PITUITARY ADRENOCORTICOTROPIC HORMONE1. Ann Intern Med. 1952;36:1–38. doi: 10.7326/0003-4819-36-1-1
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Published: Ann Intern Med. 1952;36(1):1-38.
Endocrine and Metabolism, Neurology, Pituitary Disorders, Rheumatology.
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